U.S., March 28 -- ClinicalTrials.gov registry received information related to the study (NCT07494084) titled 'Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance' on March 09.
Brief Summary: The purpose of this study is to examine the impact of timed cortisol release or differently timed cortisol rhythms on insulin resistance in both men and women undergoing sleep restriction. Chronic sleep loss is highly prevalent, affecting 1 in 3 adults in the US. Chronic sleep loss causes stress which induces insulin resistance and leads to obesity and type 2 diabetes. Many factors contribute to sleep loss including shift work, environmental disturbances, sleep/circadian disorders and comorbid medical and mental health conditions. ...