U.S., March 14 -- ClinicalTrials.gov registry received information related to the study (NCT07470684) titled 'Skin Involvement in Dupuytren Surgical Treatment Outcome' on April 18, 2025.
Brief Summary: Palmar skin is often retracted in Dupuytren disease (DD), making surgical management challenging and skin-preserving surgery difficult. Based on clinical experience in DD surgery and outcome, it is suspected that recurrence may be associated with such retracted skin. Possibly, this is due to presence and persistence of aligned myofibroblasts (MF), fixed to the deepest dermal layers. This interventional study aims to investigate the pathophysiological involvement of palmar skin in Dupuytren disease, and its implications for prognostics and tr...