U.S., March 5 -- ClinicalTrials.gov registry received information related to the study (NCT07449442) titled 'SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty' on Feb. 27.
Brief Summary: This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet x neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.
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