U.S., Nov. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07919054) titled 'Serum Estradiol and Endometrial Thickness After Bariatric Surgery in Postmenopausal Women With Obesity' on Oct. 31.
Brief Summary: Obesity changes how the body produces and processes estrogen. After menopause, higher estrogen exposure is linked to thickening of the lining of the womb (endometrium) and a higher risk of endometrial cancer. Bariatric (weight-loss) surgery produces large and lasting weight loss, but how it changes estradiol levels and the endometrium in postmenopausal women is not well described.
This prospective cohort study will follow 78 postmenopausal women with obesity who are eligible for bariatric surgery at Cair...