U.S., June 13 -- ClinicalTrials.gov registry received information related to the study (NCT07645157) titled 'Sertraline Combined With Multi-Strain Probiotics for Adolescent Depression' on June 09.
Brief Summary: The objective of this clinical trial is to evaluate the efficacy and safety of sertraline combined with multi-strain probiotics in adolescents aged 12-18 with major depressive disorder. The primary research question is whether sertraline combined with multi-strain probiotics is superior to sertraline combined with placebo in alleviating depressive symptoms and improving mood symptoms in adolescents. If there is a control group: researchers will compare sertraline combined with multi-strain probiotics with sertraline combined with p...