Clinical Trial: Selective Nerve Root Block Versus Sham to Reduce Surgery for Lumbar Disc Herniation

U.S., Oct. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07895589) titled 'Selective Nerve Root Block Versus Sham to Reduce Surgery for Lumbar Disc Herniation' on Oct. 17.

Brief Summary: The SELDISC trial will investigate whether a selective nerve root block can reduce the need for surgery in adults with a herniated disc in the lower back. A herniated disc can irritate a nerve and cause pain that travels down the leg. A nerve root block delivers a local anaesthetic and a corticosteroid near the affected nerve to relieve pain and inflammation.

The study will include 262 adults aged 18-66 years who have persistent leg symptoms despite non-surgical treatment and have been assessed by a spine surgeon as eligi...