U.S., Aug. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07745374) titled 'Safety and Feasibility of DBS for Bipolar Depression' on July 29.
Brief Summary: This study addresses a critical unmet need in the treatment of bipolar disorder by investigating whether Subcallosal Cingulate (SCC) Deep Brain Stimulation (DBS) can safely and effectively treat treatment-resistant bipolar depression without inducing manic switches. The researchers propose to accomplish this by incorporating monitoring of the SCC local field potentials (LFP) for depression tracking and amygdala LFP monitoring for mania prediction while treating Bipolar I patients with SCC DBS Stimulation. This approach could establish a new paradigm for ...