U.S., May 20 -- ClinicalTrials.gov registry received information related to the study (NCT07596485) titled 'RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal Neuralgia' on April 17.

Brief Summary: The goal of this study is to evaluate if KRIYA-748 (RP-008) is safe, tolerable, and preliminary effective in treating trigeminal neuralgia (TN) when used in combination with varenicline tartrate. The study will also assess what doses of RP-008 are safe and tolerable for participants and how the severity of participants' TN pain and frequency of facial pain attacks are affected.

Study Start Date: June, 2026

Study Type: INTERVENTIONAL

Condition: Trigeminal Neuralgia

Intervention: GENETIC: RP-008

RP-008 will be...