Clinical Trial: Role of Dyspnea in the Progression of Pediatric Acute Respiratory Distress Syndrome

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07750288) titled 'Role of Dyspnea in the Progression of Pediatric Acute Respiratory Distress Syndrome' on Aug. 01.

Brief Summary: Pediatric acute respiratory distress syndrome (ARDS) is a life-threatening clinical syndrome, and dyspnea is its key symptom. Strenuous respiratory effort is a "second hit" for ARDS lungs, inducing changes in regional lung aeration and amplifying lung damage in preclinical studies, a phenomenon known as "patient self-inflicted lung injury". In a clinical setting, clinicians are concerned about the possible connection between dyspnea and ARDS progression based on indirect evidence, such as the worse outcomes associated with ...