Clinical Trial: Reverse Remodeling of the Pulmonary Vasculature: a Longitudinal, Investigational Study of the Effects of Sotatercept.

U.S., March 24 -- ClinicalTrials.gov registry received information related to the study (NCT07487441) titled 'Reverse Remodeling of the Pulmonary Vasculature: a Longitudinal, Investigational Study of the Effects of Sotatercept.' on March 02.

Brief Summary: The goal of this study is to learn more about how sotatercept works and if it helps the lung arteries become healthier. Sotatercept will be associated with the following:

1. Improvement in capillary blush, reduce the tapering and tortuosity of affected vessels on pulmonary wedge angiography and decreased wall thickness on intravascular ultrasound in previously affected areas.

2. Improvement in previously poorly or non-perfused areas rather than increased perfusion to previously perfuse...