U.S., July 11 -- ClinicalTrials.gov registry received information related to the study (NCT07695363) titled 'Restrictive Fluid Management In Liver Transplantation (REFIL)' on June 15.

Brief Summary: The goal of the REFIL-2 study is to evaluate the effectiveness of a low splanchnic blood volume restrictive fluid management strategy (a strategy that involves limiting fluid administration and prioritizing the use of medications that raise blood pressure during surgery, combined with phlebotomy) in improving patients' recovery after surgery. The study compares the low splanchnic blood volume restrictive fluid management strategy to an optimized cardiac-output liberal fluid management strategy (which involves administering more fluids to raise ...