U.S., May 19 -- ClinicalTrials.gov registry received information related to the study (NCT07594483) titled 'Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium' on May 08.

Brief Summary: The objective of this study is to evaluate the safety, tolerability, and preliminary efficacy of the Motif eXternally powered Cortical Stimulation (XCS) System when used as indicated for treatment-resistant depression (TRD).

Study Start Date: May, 2026

Study Type: INTERVENTIONAL

Condition: Major Depressive Disorder

Intervention: DEVICE: Motif XCS System

The Motif XCS System is a programmable device that delivers stimulation through surface electrodes implanted in a burr hole in the skull, positioned over the left dorsola...