Clinical Trial: Radiomics Subtyping to Guide Surgery vs. Maintenance Therapy After HCC Downstaging

U.S., May 13 -- ClinicalTrials.gov registry received information related to the study (NCT07581769) titled 'Radiomics Subtyping to Guide Surgery vs. Maintenance Therapy After HCC Downstaging' on May 06.

Brief Summary: The goal of this observational study is to learn about the long-term treatment outcomes for patients with initially unresectable hepatocellular carcinoma (HCC) who achieve successful downstaging with the combination therapy of TACE, lenvatinib, and a PD-1 inhibitor. The main questions it aims to answer are:

Can distinct disease subtypes be identified in successfully downstaged patients using radiomics and clinical data?

Do these different subtypes show significant differences in long-term outcomes, such as recurrence-free s...