Clinical Trial: RADIATE-HF - Efficacy and Safety of Cardiac Radiation in Advanced Heart Failure: an Exploratory Single-Arm Study

U.S., Aug. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07770230) titled 'RADIATE-HF - Efficacy and Safety of Cardiac Radiation in Advanced Heart Failure: an Exploratory Single-Arm Study' on Aug. 12.

Brief Summary: The RADIATE-HF study is a prospective, interventional, single-center, open-label, non-randomized study conducted at the Rennes University Hospital.

The goal of this proof-of-concept trial is to demonstrate that low-dose cardiac radiation therapy (5 Gy) improves left ventricular function by more than 5% in the medium term in patients with advanced or end-stage heart failure.

The primary endpoint is the difference between the baseline value and the 6-month value of the FEVG as assessed by cardi...