U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07663695) titled 'Propofol vs. Ciprofol for Anesthesia Induction in Frail Elderly Patients' on June 17.
Brief Summary: Post-induction hypotension (PIH) is a common and critical complication during general anesthesia, particularly in frail elderly patients whose physiological reserves are significantly diminished. PIH is strongly associated with adverse postoperative outcomes, including acute kidney injury (AKI) and myocardial injury. Propofol is the most widely used induction agent but frequently induces circulatory depression. Ciprofol, a novel anesthetic agent developed by optimizing the molecular structure of propofol, has demonstrated improved he...