Clinical Trial: PROMOTE: Effects of 5-HT4 Agonism on Cognition and Sleep in Peopl With Low Mood

U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07848477) titled 'PROMOTE: Effects of 5-HT4 Agonism on Cognition and Sleep in Peopl With Low Mood' on Sept. 23.

Brief Summary: Serotonin is a chemical in the brain that plays an important role in mood, sleep, and other functions. It works by attaching to different types of serotonin receptors on brain cells. These receptors act like "locks", with serotonin acting like a "key". Different types of serotonin receptors have different effects in the brain.

Prucalopride is a licensed medication used to treat constipation. It acts on a particular serotonin receptor, called the serotonin 4 receptor. Researchers are interested in this receptor because underst...