U.S., April 9 -- ClinicalTrials.gov registry received information related to the study (NCT07518225) titled 'Pre-Extubation Bupivacaine for Pain Control After Orthognathic Surgery' on April 02.
Brief Summary: This study aims to evaluate whether injecting a long-acting local anesthetic (bupivacaine) at surgical sites before awakening from anesthesia can reduce pain and the need for opioid medications after orthognathic surgery. Orthognathic surgery is a major procedure that can cause significant postoperative pain, often requiring opioid analgesics, which may lead to side effects such as nausea, vomiting, and drowsiness. In this randomized clinical study, patients undergoing jaw surgery received either standard care or additional bupivacain...