U.S., July 2 -- ClinicalTrials.gov registry received information related to the study (NCT07678567) titled 'Pomegranate Dietary Supplements in AUD and ALD' on June 24.
Brief Summary: The goal of this project is to determine an individual's ability to generate active gut microbial metabolites called urolithins upon consumption of pomegranate dietary supplements. We, and others, reported that urolithins are the major active metabolites that are responsible for the beneficial activities that are rendered from eating pomegranates, berries, or walnuts. However, the production of urolithins from the parent compound ellagic acid (EA) is dependent upon the presence of certain bacteria in the human gut. In this trial, we propose to investigate vari...