Clinical Trial: Polynucleotides and Hyaluronic Acid vs Enamel Matrix Proteins in the Treatment of Intrabony Defects

U.S., May 16 -- ClinicalTrials.gov registry received information related to the study (NCT07589959) titled 'Polynucleotides and Hyaluronic Acid vs Enamel Matrix Proteins in the Treatment of Intrabony Defects' on May 11.

Brief Summary: The goal of this clinical trial is to compare two periodontal regenerative treatments in adults with Stage III or IV periodontitis and infrabony periodontal defects >=3 mm.

The study aims to determine whether hyaluronic acid and polynucleotides (Regenfast(R)) combined with bovine bone graft material (Bio-Oss(R)) provides similar or improved periodontal regeneration compared with enamel matrix derivative proteins (Emdogain(R)) combined with Bio-Oss(R).

Researchers will evaluate:

* Periodontal healing and bo...