U.S., April 1 -- ClinicalTrials.gov registry received information related to the study (NCT07503509) titled 'Physiological Study of High PEEP in Noninvasive Ventilation' on March 21.
Brief Summary: To investigate the physiological effects of high positive end-expiratory pressure (PEEP) during noninvasive ventilation in patients with hypoxemic respiratory failure, and to elucidate the mechanisms underlying high PEEP-induced improvement in oxygenation.
Study Start Date: March 26, 2024
Study Type: INTERVENTIONAL
Condition:
Respiratory Failure With Hypoxia
Intervention:
PROCEDURE: high PEEP
First, PEEP was set at 5 cmH₂O, and inspiratory pressure was adjusted to achieve a target tidal volume of 6-8 mL/kg. Fraction of inspired oxyg...