U.S., July 17 -- ClinicalTrials.gov registry received information related to the study (NCT07706686) titled 'Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection' on July 15.
Brief Summary: Background:
Dengue is a viral disease spread by mosquitoes. Most people bitten by mosquitoes carrying dengue viruses do not get sick, but severe cases can cause shock, internal bleeding, and death. There are no treatments for dengue. To develop treatments, researchers need to understand more about what dengue viruses do in the body.
Objective:
To infect healthy people with a mild dengue virus to study how their body responds.
Eligibility:
People ages 18 ...