Clinical Trial: Pharmacokinetics of Oral Zoliflodacin 3 g in Healthy Lactating Women

U.S., Nov. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07926997) titled 'Pharmacokinetics of Oral Zoliflodacin 3 g in Healthy Lactating Women' on Oct. 22.

Brief Summary: This is a single-arm clinical trial to evaluate the PK profile in breast milk and plasma after a single oral dose of zoliflodacin in healthy lactating women.

Eligible participants who have been actively breastfeeding or expressing milk for at least 4 weeks postpartum will receive a single dose of zoliflodacin administered as an oral suspension with food.

Breast milk and plasma samples will be collected at predefined time points for up to 48 hours after dosing to characterize zoliflodacin concentrations and estimate drug exposure in bre...