Clinical Trial: Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment

U.S., April 25 -- ClinicalTrials.gov registry received information related to the study (NCT07550634) titled 'Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment' on April 11.

Brief Summary: This is a Phase I, single-center, open-label, parallel-group study. A single oral dose of MDR-001, a GLP-1 receptor agonist, will be administered to participants with mild (Child-Pugh A) or moderate (Child-Pugh B) hepatic impairment and to matched healthy controls. The study aims to evaluate the pharmacokinetics and safety of MDR-001 in these populations. Primary pharmacokinetic endpoints include AUC and Cmax; safety endpoints include adverse events, vital signs, ECG, and laboratory assessments.

Study Start Date: June 01

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