U.S., May 16 -- ClinicalTrials.gov registry received information related to the study (NCT07591038) titled 'PET/CT Imaging in Carriers of TTR Mutations' on May 08.
Brief Summary: The purpose of this study is to determine if TTR gene carriers have early signs of a type of heart disease called amyloidosis using a new radiotracer dye (iodine-124 evuzamitide, I-124E).
Participants will undergo a screening that includes a medical history review and completion of quality-of-life surveys. Once screening is complete, participants will undergo an imaging test called a positron emission tomography (PET) scan combined with computed tomography (PET/CT) to make images of the body. The new radiotracer dye (I-124E, a radioactive contrast) will be used d...