U.S., May 15 -- ClinicalTrials.gov registry received information related to the study (NCT07586150) titled 'Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)' on April 09.

Brief Summary: This randomized, rater-blind, multicenter clinical trial will evaluate whether a personalized pharmaco-lifestyle intervention improves mental functioning in adults with severe mental illness, including schizophrenia, bipolar disorder, or major depressive disorder. Participants will be randomized to either a modular individualized intervention program or a structured psychoeducation control condition. The individualized intervention may include physical exercise, an anti-inflammatory diet, sleep intervention, social presc...