Clinical Trial: Pediatric Congenital Adrenal Hyperplasia Management: Regret and Long-term Outcomes

U.S., Aug. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07781267) titled 'Pediatric Congenital Adrenal Hyperplasia Management: Regret and Long-term Outcomes' on Aug. 19.

Brief Summary: Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is a chronic endocrine disorder, often diagnosed in the neonatal period. Severe forms may lead to genital virilization in afected girls and adrenal crises. Management includes lifelong hormone replacement therapy and, historically, early genital surgery, although recent guidelines recommend delaying non-urgent procedures to preserve patient autonomy.This study hypothesizes that pediatric management, particularly early surgical interventions, may influence...