U.S., Sept. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07837869) titled 'PACE: Prostacyclin AntiCoagulation in ECMO' on Sept. 11.
Brief Summary: Extracorporeal membrane oxygenation (ECMO) is a machine that temporarily supports the heart and/or lungs and is a critical rescue therapy for refractory cardiac and respiratory failure in pediatric populations. Despite technological advancements, the contact between blood and the artificial surface of the ECMO circuit often triggers blood clotting that requires blood thinning medications while on ECMO. The current standard of care is to use medications that have little effect on platelets, a part of the clotting system that can be activated by parts of the ECMO...