U.S., April 25 -- ClinicalTrials.gov registry received information related to the study (NCT07551297) titled 'Ozone Therapy After Open Flap Debridement in Periodontitis' on April 18.
Brief Summary: Periodontitis is a chronic inflammatory disease characterized by the destruction of supporting periodontal tissues. Open flap debridement (OFD) is a commonly used surgical approach for the treatment of deep periodontal pockets when non-surgical therapy is insufficient. However, complete elimination of pathogenic microorganisms remains challenging.
Ozone therapy has been proposed as an adjunctive treatment due to its antimicrobial, anti-inflammatory, and wound healing properties. This randomized split-mouth clinical trial aims to evaluate the cl...