Clinical Trial: Outpatient Hypertonic Saline and Loop Diuretic Combination Therapy in Cardiorenal

U.S., May 20 -- ClinicalTrials.gov registry received information related to the study (NCT07596329) titled 'Outpatient Hypertonic Saline and Loop Diuretic Combination Therapy in Cardiorenal' on Feb. 24.

Brief Summary: Congestive heart failure (CHF) remains a major cause of morbidity, rehospitalization, and mortality worldwide, particularly among elderly and polymorbid patients. Systemic congestion is its most characteristic clinical manifestation and the leading cause of hospitalization for acute heart failure. Standard treatment relies on loop diuretics, primarily furosemide, to reduce fluid overload and alleviate congestive symptoms. However, in clinical practice, many patients exhibit an inadequate diuretic response or resistance to fur...