U.S., May 2 -- ClinicalTrials.gov registry received information related to the study (NCT07561307) titled 'Optimizing Stimulation Parameters for Electroconvulsive Therapy' on March 25.
Brief Summary: The goal of this clinical trial is to improve how electroconvulsive therapy (ECT) stimulation settings are chosen. Researchers will use real-time brain monitoring to measure both seizures and a recently identified brain event called cortical spreading depolarization (CSD).
The main questions it aims to answer are:
What is the best way to increase ECT stimulation settings? How do different pulse settings affect the brain's response? Can certain settings produce CSD without causing a seizure?
Participants already receiving ECT as part of thei...