U.S., March 28 -- ClinicalTrials.gov registry received information related to the study (NCT07496281) titled 'OPTIA-AF Trial: Rhythm-Guided Antithrombotic Strategy After AF Ablation' on March 15.
Brief Summary: The OPTIA-AF trial is a prospective, multicenter randomized controlled trial designed to evaluate a rhythm-guided antithrombotic strategy in patients with atrial fibrillation (AF) who maintain durable sinus rhythm after catheter ablation and have a history of prior drug-eluting stent (DES) implantation. Current guidelines generally recommend long-term oral anticoagulation (OAC) in patients with AF, even after successful ablation, while antiplatelet therapy remains essential for prevention of coronary ischemic events following percut...