U.S., Oct. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07895472) titled 'Opioid Reduction and Enhanced Recovery in Orthopaedic Surgery (OREOS)-Knee' on Oct. 19.
Brief Summary: Knee replacements are the second most common surgery in Canada. Most patients recover very well but research consistently shows that 1 in 5 patients still have pain many months after surgery. Doctors often prescribe opioid medications for pain after surgery (e.g. Percocet, hydromorphone, codeine). These medications can be helpful for some people, but they can also be dangerous, particularly when used for a long time. Many patients don't like the way opioids make them feel and would prefer alternative pain management strategies. Som...