U.S., March 24 -- ClinicalTrials.gov registry received information related to the study (NCT07489001) titled 'Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery' on Dec. 11, 2025.
Brief Summary: This prospective, observational, non-randomized clinical study aims to evaluate the intraoperative and postoperative effects of opioid-free multimodal anesthesia compared with opioid-containing anesthesia methods in adult patients undergoing lumbar spinal surgery. Patients will be managed according to routine clinical practice and assigned to one of three groups based on the analgesic strategy used by the attending anesthesiologist: (1) opioid-free anesthesia using multimodal agents and/or erector spinae plane (ESP) block; (2)...