U.S., June 9 -- ClinicalTrials.gov registry received information related to the study (NCT07632144) titled 'Ondansetron Versus Lidocaine for Preventing Pain on Propofol Injection.' on June 02.
Brief Summary: This is a prospective, single-center, randomized, double-blind controlled trial involving patients scheduled for elective surgery requiring general anesthesia with propofol induction. Participants are randomly assigned to one of three groups: the ondansetron group (8 mg IV), the lidocaine group (40 mg IV), or the control group (0.9% normal saline placebo). Study medications are administered intravenously over 5 minutes, ending 1 minute before anesthetic induction.
the goal: To assess the efficacy of intravenous ondansetron versus lido...