U.S., June 25 -- ClinicalTrials.gov registry received information related to the study (NCT07666724) titled 'Oncology Treatment Related Ocular Surface Changes' on June 09.
Brief Summary: clinical trial
The goal of this clinical trial is to learn if drug trastuzumab works to treat HER2 positive mamma carcinomas without causing dry eye related ocular surface changes in adults. The main questions it aims to answer are:
Does trastuzumab increase the dry eye related subjective symptoms? Does trastuzumab cause increased tear film instability and corneal epithelial staining (Oxford score), and lipid layer deterioration? Is a dose-dependent ocular surface effect identifiable attributable to trastuzumab and their modification by patient age?
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