U.S., April 21 -- ClinicalTrials.gov registry received information related to the study (NCT07539766) titled 'OBESE-HFpEF: Towards Preventing Obesity Related HFpEF' on Jan. 30.
Brief Summary: Obesity, severe overweight, is a growing problem worldwide and increases the risk of heart failure, especially a type called heart failure with preserved ejection fraction (HFpEF).
In HFpEF, the heart becomes stiffer. This makes it harder for the heart to fill with blood, which can lead to shortness of breath during physical activity.
In the Netherlands, 15% of the population has obesity. In South Limburg, this is even higher at 19%. Among people with HFpEF, obesity is much more common: about 50% of these patients have obesity.
Life expectancy in p...