U.S., Aug. 12 -- ClinicalTrials.gov registry received information related to the study (NCT07758894) titled 'Non-Intubated Anesthesia for Adult Heart Transplantation' on July 31.
Brief Summary: This prospective, multicenter, randomized controlled trial aims to evaluate whether non-intubated spontaneous ventilation anesthesia (NISVA) supported by a supraglottic airway can reduce cardiopulmonary complications and promote postoperative recovery in adults undergoing isolated orthotopic heart transplantation. Approximately 220 participants will be randomly assigned in a 1:1 ratio to either the NISVA group or the conventional endotracheal general anesthesia group. The study will primarily evaluate a cardiopulmonary composite endpoint within 30 d...