Clinical Trial: Neuroprotective Impact of Dexmedetomidine Versus Propofol on Intracranial Pressure Monitoring in Adult Traumatic Brain Injury Patients

U.S., Sept. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07807579) titled 'Neuroprotective Impact of Dexmedetomidine Versus Propofol on Intracranial Pressure Monitoring in Adult Traumatic Brain Injury Patients' on Sept. 02.

Brief Summary: To investigate whether dexmedetomidine or propofol is more effective in controlling intracranial pressure (ICP) (assessed via optic nerve sheath diameter "ONSD" as a primary outcome) and which is more effective in suppressing lipid peroxidation (measured via malondialdehyde "MDA" as a secondary outcome). This double-blind randomized controlled trial aims to bridge this research gap by evaluating the biochemical neuroprotective efficacy alongside the clinical outcomes of b...