U.S., May 15 -- ClinicalTrials.gov registry received information related to the study (NCT07587268) titled 'Molecular Profiling for Risk Stratification in Appendiceal Cancer' on May 04.
Brief Summary: This study investigates integrated epigenetic and epitranscriptomic features of appendiceal cancer using archived tumor tissue specimens from the same patient cohort. The study includes DNA methylation profiling and m6A epitranscriptomic profiling to define molecular subtypes, evaluate associations with clinicopathologic features, and develop molecular risk scores for prognostic stratification. The primary goal is to determine whether DNA methylation- and m6A-based molecular features can complement conventional histopathologic grading and imp...