Clinical Trial: Molecular Imaging to Identify Predictors of Aortic Valve Disease Activity

U.S., Sept. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07819344) titled 'Molecular Imaging to Identify Predictors of Aortic Valve Disease Activity' on Sept. 08.

Brief Summary: This is a prospective study that aims to devlop clinical calculators that will report on the underlying rate of aortic valve calcification. To do so, baseline 18FNaF PET/CT will be obtained to measure AS disease activity, the rate of active microcalcification. Using these data, multi-omics prediction models and calculator tools will be developed to provide an index of ongoing disease activity (active calcification). Follow-up imaging (both echo and CT) will be performed 1 year after baseline imaging, to assess progression. We will...