U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07435636) titled 'Modulation of Stem Cell Differentiation in Individuals With High Risk Clonal Haematopoiesis' on Feb. 17.
Brief Summary: Clonal hematopoiesis (CH) is characterized by the overproduction of blood cells derived from a single hematopoietic stem and progenitor cell (HSPC) harboring certain somatic mutations. It is linked to serious outcomes, including cardiovascular disease, myeloid neoplasm (MN), and increased mortality.
Clonal Cytopenia of Uncertain Significance (CCUS) is a CH subtype characterized by associated persistent cytopenia. It affects approximately 10 % of people over 70 and is the most advanced precursor state with the high...