U.S., April 25 -- ClinicalTrials.gov registry received information related to the study (NCT07549230) titled 'Model-Informed Precision Dosing of Tacrolimus in Pediatric Kidney Transplantation' on April 15.
Brief Summary: The purpose of this study is to develop a novel and applicable dosing algorithm that helps support the clinical decision to achieve tacrolimus levels within the optimal immunosuppression range despite sparse sampling in routine clinical practice in pediatric kidney transplantation. This clinical decision support tool (CDST) is based on a hybrid population pharmacokinetics-machine learning approach aiming for tacrolimus dose individualization and reducing the risk of acute graft rejection.
Study Start Date: June 01
Study ...