U.S., April 21 -- ClinicalTrials.gov registry received information related to the study (NCT07538284) titled 'MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES)' on May 30, 2025.
Brief Summary: This study aims to determine whether, compared with placebo, the nighttime self-administration of a nasal dexmedetomidine is effective at inducing sleep and preventing postoperative delirium in high-risk patients.
Study Start Date: May 01
Study Type: INTERVENTIONAL
Condition:
Major Abdominal Surgery
Postoperative Delirium (POD)
Sleep Disturbances
Intranasal Dexmedetomidine
Intervention:
DRUG: Dexmedetomidine
Intranasal dexmedetomidine (100 µg total: 4 sprays, 25 µg/spray; Hengrui Medicine, China) self-administere...