Clinical Trial: Microbiome and Enteric Signatures in Sepsis-associated Hepatorenal Injury

U.S., July 30 -- ClinicalTrials.gov registry received information related to the study (NCT07735182) titled 'Microbiome and Enteric Signatures in Sepsis-associated Hepatorenal Injury' on July 15.

Brief Summary: Sepsis is a major cause of morbidity and mortality in intensive care units. Sepsis-associated liver injury (SALI) and sepsis-associated acute kidney injury (S-AKI) are common complications associated with adverse clinical outcomes. Altered gut microbial diversity, microbial metabolites, intestinal barrier dysfunction, and systemic inflammation may contribute to hepato-renal injury during sepsis; however, prospective longitudinal evidence in patients with SALI and S-AKI remains limited.

This prospective, multicenter, longitudinal ob...