Clinical Trial: Mechanical Power for Ventilatory Settings in Operating Room

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07620132) titled 'Mechanical Power for Ventilatory Settings in Operating Room' on May 15.

Brief Summary: Postoperative respiratory failure (PRF) is a dreaded complication that imposes a significant burden through unplanned admission to the ICU, post discharge disability and mortality. Despite widespread implementation of intraoperative lung-protective ventilation strategies over the past decade, results remain inconsistent. Interventions targeting individual parameters like tidal volume or positive end-expiratory pressure (PEEP) have shown equivocal results. The use of high PEEP and recruitment maneuvers raises safety concerns by possible negative hem...