U.S., May 21 -- ClinicalTrials.gov registry received information related to the study (NCT07600177) titled 'Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic Cardiomyopathy' on May 07.

Brief Summary: This is an investigator-initiated two-center study. The goal of this study is to investigate the feasibility, safety and efficacy outcomes of a seamless transition from mavacamten to aficamten in patients with obstructive hypertrophic cardiomyopathy (oHCM).

Study Start Date: May 05

Study Type: INTERVENTIONAL

Condition: Hypertrophic Cardiomyopathy (HCM)

Intervention: DRUG: Aficamten

Patients will be switched from mavacamten to aficamten. Mavacamten will be stopped at enrollment, and aficamten started 2 weeks la...