U.S., Feb. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07415213) titled 'Mapping Metabolic Organ Plasticity in Energy Adaptation' on Feb. 09.
Brief Summary: Brief Summary (Plain Language)
Many people who lose weight experience a slowdown in their metabolism that is greater than expected. This response, called metabolic adaptation, makes it harder to continue losing weight or to keep weight off over time. The biological reasons for this slowdown are not fully understood.
Some organs in the body, especially the liver and kidneys, use a large amount of energy even when the body is at rest. Although these organs make up only a small portion of body weight, they account for a large share of daily energy use...