U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07477730) titled 'Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty.' on March 13.
Brief Summary: Total knee arthroplasty (TKA) is one of the most common orthopedic surgical procedures and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
Optimal postoperative pain management after TKA is not fully defined. While multimodal analgesia is standard, the choice of associated regional anesthesia techniques is debated.
Local infiltration analgesia (LIA) is widely used and provides effective pain relief without impairing early mobilization.
Peripheral nerve blocks have...