U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07537946) titled 'Local Consolidation After Sintilimab Plus Lenvatinib for Metastatic Liver Cancer' on April 12.
Brief Summary: This study evaluates whether comprehensive local consolidative therapy added to continued sintilimab plus lenvatinib improves survival compared with continued sintilimab plus lenvatinib alone in patients with oligo-extrahepatic metastatic hepatocellular carcinoma. All enrolled participants receive induction treatment with sintilimab plus lenvatinib for 4 cycles. Participants who achieve disease control and are confirmed by central multidisciplinary review to be feasible for complete consolidation are randomized in a 1:1 rat...