Clinical Trial: LISA vs Endotracheal Surfactant in Preterm Neonates: A Lung Ultrasound Distribution Study

U.S., April 8 -- ClinicalTrials.gov registry received information related to the study (NCT07514481) titled 'LISA vs Endotracheal Surfactant in Preterm Neonates: A Lung Ultrasound Distribution Study' on March 27.

Brief Summary: This prospective, non-randomized, unblinded pilot study evaluates and compares the intrapulmonary distribution of exogenous surfactant in preterm neonates when administered via Less Invasive Surfactant Administration (LISA) versus conventional endotracheal intubation (ETT). Lung ultrasound (LUS) will be utilized to assess the pioneer Surfactant Distribution Homogeneity Index (SDHI) to quantify the evenness and extent of surfactant-induced lung aeration. Secondary objectives include evaluating changes in LUS scores, ...